See The Simparica Trio Difference
*As a direct result of killing deer ticks
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| Prevents Lyme Infections* |  |
| Prevents Heartworm Disease | |
| Kills 6 Types of Ticks | |
| Kills Fleas | |
| Kills Fleas Before They Can Lay Eggs | |
| Treats Roundworms | |
| Treats Hookworms | |
Approved for Dogs | |
Approved for Dogs | |
| Heartgard® Plus1 | NexGard®2 | Bravecto®3 | Credelio®4 | Interceptor® Plus5 |
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5 types |
5 types |
4 types |
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6 mo.+ |
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4lbs+ |
4.4lbs + |
4.4lbs + |
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Important Safety Information: Use with caution in dogs with a history of seizures. Simparica Trio contains sarolaner, a member of the isoxazoline class which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders. The safe use of Simparica Trio has not been evaluated in breeding, pregnant, or lactating dogs. The most frequently reported adverse reactions in clinical trials were vomiting and diarrhea. See full Prescribing Information.
SIMPARICA TRIO is indicated for the prevention of heartworm disease caused by Dirofilaria immitis and for the treatment and control of roundworm (immature adult and adult Toxocara canis and adult Toxascaris leonina) and hookworm (L4, immature adult, and adult Ancylostoma caninum and adult Uncinaria stenocephala) infections. SIMPARICA TRIO kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations, and the treatment and control of tick infestations with Amblyomma americanum (lone star tick), Amblyomma maculatum (Gulf Coast tick), Dermacentor variabilis (American dog tick), Ixodes scapularis (black-legged tick), Rhipicephalus sanguineus (brown dog tick), and Haemaphysalis longicornis (Asian longhorned tick) for one month in dogs and puppies 8 weeks of age and older, and weighing 2.8 pounds or greater. SIMPARICA TRIO is indicated for the prevention of Borrelia burgdorferi infections as a direct result of killing Ixodes scapularis vector ticks.
References:
- Heartgard® Plus [package insert], Duluth, GA: Boehringer Ingelheim Group; 2019
- NexGard® [package insert], Duluth, GA: Boehringer Ingelheim Group; 2023.
- Bravecto® [package insert], Summit, NJ: Merck & Co; 2023.
- Credelio® [package insert], Greenfield, IN: Elanco; 2020.
- Interceptor® Plus [package insert]. Greenfield, IN: Elanco; 2021.
Heartgard and NexGard are registered trademarks of Boehringer Ingelheim Animal Health USA Inc. Bravecto is a registered trademark of Intervet Inc. d/b/a Merck Animal Health. Credelio, Interceptor, and Trifexis are registered trademarks of Elanco or its affiliates.
ZPC-01080R7
